(6R)-2-tert-Butyl-6-[(4R,5S)-3-isopropyl-4-methyl-5-phenyloxazolidin-2-yl]phenol
نویسندگان
چکیده
In the title compound, C(23)H(31)NO(2), the lone pair on the nitro-gen atom is oriented to facilitate intra-molecular hydrogen bonding with the hydr-oxy group residing on the phenyl substituent. The five-membered ring adopts an envelope confornmation with the O atom at the flap. The absolute stereochemistry was verified by measurement of optical activity using a digital polarimeter.
منابع مشابه
(6S)-2,4-Di-tert-butyl-6-[(4S,5R)-3-isopropyl-4-methyl-5-phenyloxazolidin-2-yl]phenol
The title oxazolidine compound, C(27)H(39)NO(2), was synthesized from N-isopropyl-norephedrine. The dihedral angle between the aromatic rings is 70.33 (5)°. The N atom of the heterocycle is oriented to allow intra-molecular O-H⋯N hydrogen bonding with the hydr-oxy substituent.
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